약학대학 - 약학대학

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관심분야

Peptide and protein drug delivery 
Nanoparticulate drug delivery systems 
Polymer conjugation technology for long-acting biopharmaceuticals 
Inhalation delivery systems

학력

  • (Ph.D.) 1995.03-1999.02 School of Pharmacy, Sungkyunkwan University (Pharmacy)

약력/경력

  • 2004.03-2006.06 성균관대학교 약학연구소 선임연구원
  • 2006.07-2007.08 Department of pharmaceutics and pharmaceutical chemistry, University of Utah Post-Doc. fellow
  • 2007.09-2011.08 부산대학교 약학대학 조교수
  • 2008.01-2008.02 한국약제학회 총무간사
  • 2009.10-Present Korean American Pharmaceutical Scientists Association (KAPSA) 편집간사
  • 2010.01-Present 한국약제학회 학술간사
  • 2011.09-Present 성균관대학교 약학대학 부교수
  • 2011.10-Present Asian Journal of Pharmaceutical Sciences Editorial, Board Member
  • 2011.10-Present Archives of Pharmacal Research, Associate Editor
  • 2014.09-Present 성균관대학교 약학연구소장

학술지 논문

  • (2022)  Hydroxypropyl-13-cyclodextrin-based solid dispersed granules: A prospective alternative to conventional solid dispersion.  INTERNATIONAL JOURNAL OF PHARMACEUTICS.  628,  1
  • (2022)  Development of a pH-Responsive Polymer Based on Hyaluronic Acid Conjugated with Imidazole and Dodecylamine for Nanomedicine Delivery.  MACROMOLECULAR RESEARCH.  30,  8
  • (2022)  pH-Sensitive Twin Liposomes Containing Quercetin and Laccase for Tumor Therapy.  BIOMACROMOLECULES.  23,  9
  • (2022)  Delivery of Molecules Using Nanoscale Systems for Cancer Treatment and/or Diagnosis.  PHARMACEUTICS.  14,  4
  • (2021)  Hyperthermal paclitaxel-bound albumin nanoparticles co-loaded with indocyanine green and hyaluronidase for treating pancreatic cancers.  ARCHIVES OF PHARMACAL RESEARCH.  44,  2
  • (2021)  Tumor-Targeting Liposomes with Transient Holes Allowing Intact Rituximab Internally.  BIOMACROMOLECULES.  22,  2
  • (2021)  Comparative study between high-pressure homogenisation and Shirasu porous glass membrane technique in sildenafil base-loaded solid SNEDDS: Effects on physicochemical properties and in vivo characteristics.  INTERNATIONAL JOURNAL OF PHARMACEUTICS.  592,  1
  • (2020)  Transferrin-Conjugated pH-Responsive gamma-Cyclodextrin Nanoparticles for Antitumoral Topotecan Delivery.  PHARMACEUTICS.  12,  11
  • (2020)  Highly Red Light-Emitting Erbium- and Lutetium-Doped Core-Shell Upconverting Nanoparticles Surface-Modified with PEG-Folic Acid/TCPP for Suppressing Cervical Cancer HeLa Cells.  PHARMACEUTICS.  12,  11
  • (2020)  Alendronate/cRGD-Decorated Ultrafine Hyaluronate Dot Targeting Bone Metastasis.  BIOMEDICINES.  8,  11
  • (2020)  An On-Demand pH-Sensitive Nanocluster for Cancer Treatment by Combining Photothermal Therapy and Chemotherapy.  PHARMACEUTICS.  12,  9
  • (2020)  Development ofpH-responsive cyclodextrin nanoparticles for tumor-specific photodynamic therapy.  POLYMERS FOR ADVANCED TECHNOLOGIES.  31,  12
  • (2020)  Indocyanine Green and Curcumin Co-Loaded Nano-Fireball-Like Albumin Nanoparticles Based on Near-Infrared-Induced Hyperthermia for Tumor Ablation.  INTERNATIONAL JOURNAL OF NANOMEDICINE.  15, 
  • (2020)  Cyclic RGD-Conjugated Hyaluronate Dot Bearing Cleavable Doxorubicin for Multivalent Tumor Targeting.  BIOMACROMOLECULES.  21,  6
  • (2020)  Tumor-Homing pH-Sensitive Extracellular Vesicles for Targeting Heterogeneous Tumors.  PHARMACEUTICS.  12,  4
  • (2020)  Emerging NIR light-responsive delivery systems based on lanthanide-doped upconverting nanoparticles.  ARCHIVES OF PHARMACAL RESEARCH.  43,  1
  • (2019)  Immune-triggered cancer treatment by intestinal lymphatic delivery of docetaxel-loaded nanoparticle.  JOURNAL OF CONTROLLED RELEASE.  311,  1
  • (2019)  Co-delivery of D-(KLAKLAK)(2) peptide and doxorubicin using a pH-sensitive nanocarrier for synergistic anticancer treatment.  JOURNAL OF MATERIALS CHEMISTRY B.  7,  27
  • (2019)  A pH-Sensitive Polymer for Cancer Targeting Prepared by One-Step Modulation of Functional Side Groups.  MACROMOLECULAR RESEARCH.  27,  8
  • (2019)  Facile fabrication of hyaluronated starch nanogels for efficient docetaxel delivery.  JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS.  34,  4-5

특허/프로그램

  • 알부민을 포함하는, 초분자 상호작용에 기초한 자가조립 나노복합체, 이의 제조방법 및 이의 용도.  10-2016-0059605.  20181029.  대한민국
  • 폐암의 병용치료를 위한 자가조립 알부민 나노입자 및 이의 제조방법.  10-2014-0137648.  20160107.  대한민국

수상/공훈

  • Korean-American Pharmaceutical Scientists Association (KAPSA) 공로상

학술회의논문

  • (2015)  Cationized and mannose-modified HSA nanoparticles as a dual-targeting drug delivery system for treating brain cancer.  한국약제학회 국제학술대회.  대한민국
  • (2015)  Preparation and evaluation of TRAIL and paclitaxel-daul-loaded albumin nanoparticles in pancreatic cancer.  한국약제학회 국제학술대회.  대한민국
  • (2015)  Therapeutic effects of inhaled tacrolimus-bound albumin nanoparticles in a bleomycin-induced pulmnary fibrosis model.  한국약제학회 국제학술대회.  대한민국
  • (2015)  A Targeted system of TRAIL and Paclitaxel-dual-loaded albumin nanoparticels for the treatment of pancreatic cancer.  American Association of Pharmaceutical Scientists (AAPS).  미국
  • (2015)  Preparation of dual-targeting doxorubicin-loaded HSA nanoparticles and its therapeutic effect on brain tumor-bearing animals.  American Association of Pharmaceutical Scientists (AAPS).  미국
  • (2015)  Preparation and characterization of inhaled tacrolimus-bound albumin nanaoparticles in a bleomycin-induced pulmonary fibrosis.  대한약학회 국제학술대회.  대한민국
  • (2015)  Preparation and therapeutic application of albumin-based nanoparticles for the treatment of cancers.  Changbi Mountain Forum.  중국
  • (2014)  Albumin-baed nano-systems for targeted deliveyr.  The 3rd Asian Symposium on Pharmaceutical Science and Technology (ASPST 2014).  중국
  • (2014)  Albumin-based nanomaterials for targeted drug delivery.  5th FIP Pharmaceutical Sciences World Congress (PSWC).  오스트레일리아